Category: ANTI BIOTICS
Product Description
Ciprofloxacin 500 mg Tablets contain ciprofloxacin, a fluoroquinolone antibiotic used to treat selected bacterial infections. It works by inhibiting enzymes essential for bacterial DNA replication, resulting in the death of susceptible bacteria.
Ciprofloxacin is a prescription-only medicine and should be used according to a healthcare professional’s instructions.
Indications
For the treatment of infections caused by susceptible bacteria, including:
- Urinary tract infections, including complicated infections and pyelonephritis.
- Chronic bacterial prostatitis.
- Selected bacterial gastrointestinal infections, including typhoid fever.
- Skin and soft tissue infections.
- Bone and joint infections.
- Selected lower respiratory tract infections.
Treatment should consider bacterial susceptibility and local antibiotic guidelines. For uncomplicated urinary tract infections, acute sinusitis and acute exacerbations of chronic bronchitis, ciprofloxacin should be reserved for patients without suitable alternative treatment options. It does not treat viral infections.
Contraindications
Ciprofloxacin must not be used in patients with:
- Known hypersensitivity to ciprofloxacin, other quinolone antibiotics or any component of the formulation.
- Concurrent use of tizanidine.
Important precautions: Avoid use in patients with myasthenia gravis or a history of serious fluoroquinolone-related adverse reactions. Ciprofloxacin may cause serious tendon injury, peripheral nerve damage and central nervous system effects. Stop treatment and seek medical advice promptly if symptoms develop. Use during pregnancy, breastfeeding or childhood requires specific medical assessment.
Dosage and Administration
Take only as prescribed. The dose and treatment duration depend on the infection, its severity, bacterial susceptibility and kidney function.
- Adults: 500 mg every 12 hours is used for several indications; the prescriber must determine the appropriate regimen.
- Renal impairment: Dose or dosing-interval adjustment may be required.
- Swallow with water, with or without food, and maintain adequate hydration.
- Take at least 2 hours before or 6 hours after antacids, sucralfate or supplements containing calcium, magnesium, aluminium, iron or zinc.
- Avoid taking with milk, yoghurt or calcium-fortified juice alone; it may be taken with a meal containing these products.
- Follow the prescribed treatment duration and do not share antibiotics.
Key Features
- 500 mg strength for prescribed oral treatment.
- Bactericidal action against susceptible organisms.
- Antibacterial spectrum covering a range of Gram-negative and selected Gram-positive bacteria.
- Tissue distribution, including penetration into urinary and prostatic tissues.