Generic Name:
Category: ANTI BOITICS
Product Description
Sumox® contains Amoxicillin, a broad-spectrum aminopenicillin antibiotic with potent bactericidal activity against a wide range of Gram-positive and Gram-negative bacteria. It works by inhibiting bacterial cell wall synthesis, leading to rapid destruction of susceptible microorganisms.
Available as 500 mg capsules and injectable formulation, Sumox® is indicated for the treatment of a variety of bacterial infections and provides reliable efficacy in both community and hospital settings. It should be used only for infections caused by susceptible organisms and in accordance with antimicrobial stewardship principles.
Indications
Sumox® is indicated for the treatment of susceptible bacterial infections, including:
- Upper respiratory tract infections (tonsillitis, pharyngitis, sinusitis)
- Acute otitis media
- Lower respiratory tract infections, including bronchitis and community-acquired pneumonia
- Urinary tract infections, including cystitis and pyelonephritis
- Skin and soft tissue infections
- Dental infections, including dental abscesses
- Gastrointestinal infections, including typhoid and paratyphoid fever
- Bone and joint infections
- Helicobacter pylori eradication (in combination with appropriate medicines)
- Lyme disease
- Endocarditis prophylaxis in patients at risk undergoing appropriate procedures
Contraindications
Sumox® is contraindicated in patients with:
- Known hypersensitivity to amoxicillin, penicillins, or any component of the formulation.
- A history of severe immediate hypersensitivity reactions (e.g., anaphylaxis) to other β-lactam antibiotics, including cephalosporins, carbapenems, or monobactams.
- Previous serious allergic reactions associated with penicillin therapy.
Use with caution in patients with renal impairment, infectious mononucleosis, or a history of allergic disorders.
Dosage and Administration
Dosage should be individualized according to the severity of infection, patient age, body weight, and renal function.
Adults and Children ≥40 kg
Oral (Capsules):
- 250–500 mg every 8 hours for mild to moderate infections.
- 750 mg–1 g every 12 hours or 500 mg–1 g every 8 hours for more severe infections.
Injection (IV/IM):
- 500 mg to 1 g every 8 hours, depending on the severity and type of infection.
- Severe infections may require higher doses according to established treatment guidelines.
Children (<40 kg)
- 20–90 mg/kg/day in divided doses, depending on the indication and severity of infection.
Duration of Therapy
- Continue treatment for 48–72 hours after clinical improvement or as directed by the treating physician.
- For streptococcal infections, treatment should continue for at least 10 days to reduce the risk of complications.
Key Features
- Broad-spectrum aminopenicillin antibiotic
- Rapid bactericidal activity against susceptible bacteria
- Available in oral capsules and injectable formulation
- Effective for respiratory, urinary, skin, dental, gastrointestinal, bone, and joint infections
- Excellent tissue penetration
- Suitable for both outpatient and hospital management of bacterial infections
- Supports evidence-based antimicrobial therapy when used according to susceptibility patterns.