Category: ANTI BIOTICS
Product Description
Supacef® 500 mg Tablets contain Cefuroxime Axetil, an orally administered second-generation cephalosporin antibiotic. Following absorption, cefuroxime axetil is rapidly converted to active cefuroxime, which exerts bactericidal activity by inhibiting bacterial cell wall synthesis.
Supacef® Tablets provide reliable oral therapy for a broad range of community-acquired bacterial infections caused by susceptible organisms.
Indications
Supacef® Tablets are indicated for the treatment of:
- Acute bacterial sinusitis
- Acute otitis media
- Pharyngitis and tonsillitis
- Acute exacerbation of chronic bronchitis
- Community-acquired pneumonia
- Uncomplicated urinary tract infections
- Skin and soft tissue infections
- Early Lyme disease
- Uncomplicated gonorrhoea (where appropriate)
Contraindications
Supacef® Tablets are contraindicated in patients with:
- Known hypersensitivity to cefuroxime, other cephalosporins, or any component of the formulation.
- History of severe immediate hypersensitivity reactions to penicillins or other β-lactam antibiotics.
Use with caution in patients with renal impairment, gastrointestinal disorders, or a history of antibiotic-associated colitis.
Dosage and Administration
Supacef® Tablets should be taken after food to enhance absorption.
Adults
- 250–500 mg twice daily, depending on the type and severity of infection.
Examples include:
- Respiratory tract infections: 250–500 mg twice daily for 5–10 days
- Urinary tract infections: 250 mg twice daily for 5–7 days
- Skin and soft tissue infections: 250–500 mg twice daily for 7–10 days
- Early Lyme disease: 500 mg twice daily for 20 days
Children
- Dosage should be based on body weight and the severity of infection according to standard treatment guidelines.
Patients with Renal Impairment
- Dose adjustment is recommended according to renal function.
Key Features
- Oral second-generation cephalosporin antibiotic
- Broad-spectrum activity against common respiratory and urinary pathogens
- Effective against β-lactamase-producing bacteria
- Convenient twice-daily dosing
- Best absorbed when taken after meals
- Excellent clinical efficacy in respiratory, urinary, skin, and soft tissue infections
- Suitable for outpatient management of susceptible bacterial infections